Category: Technology

2017 wasn’t all bad: a good news story that will change the world forever

Now that the end is nigh for 2017, I think we’d all agree that the last twelve months have had more than their fair share of memorable moments. We’ve seen Donald Trump begin his reign of power, Kim Jong Un shoot off his shiny new intercontinental missiles, the Grenfell tower block burn down in the UK, and the bell ring for round one of the political bout that is Brexit. It’s hard to remain upbeat with a steady trickle of terrorist atrocities, a never-ending migrant crisis, and Middle East conflicts that show no sign of ending. There has, however, been a lot of good news that has slipped under the radar. This blog post is about my choice of what didn’t get the publicity it deserved. Not everyone will agree, and I’d be interested to know what other people would choose (feel free to comment below).

Get ready to say ‘bye bye’ to some very nasty diseases

The past year has witnessed some incredible advances  developments that look set to revolutionise our lives for ever – and in a very good way. My pick of this year’s most important medical breakthroughs came in the form of a new type of medical treatment called gene therapy. 2017 has seen the coming of age of a new gene editing technology that has been the talk of science town. Called CRISPR (pronounced ‘crisper’), this is an innovation that lets lab workers precisely write to and edit a person’s genetic code. It’s getting so accurate that next-generation ‘CRISPR 2.0’ (which debuted in October) has made it possible to snip and chop just as you would correct a spelling mistake on a word processor.

With this emerging therapy, it is quite possible that conditions like haemophilia and sickle cell disease will go the way of smallpox and be eradicated from planet Earth. The source of the problem – the faulty DNA code – will be fixed with a bit of genetic jiggery-pokery. Back in March, a French teenager was apparently cured of sickle cell disease with a gene therapy. It was causing him agonising ‘sickle cell crises’ in his limbs and abdomen, each bout lasting up to a week. His internal organs were also slowly failing. Now the 14-year-old boy has been “given his life back” – the genetic error he was born with has been erased.

In November, gene therapy was used for the first time in a 44-year-old man afflicted with Hunter’s Syndrome – a hereditary condition causing stunted growth, low IQ, and progressive disability. And just last week the USA drug approval authority (the FDA) gave the all-clear for gene therapy to treat a rare form of blindness. The countdown has now begun until we create ‘cures’ for the evilest of degenerative diseases, like Huntingdon’s disease and Motor Neurone disease.

It doesn’t stop with the hereditary conditions that you are born with. Researchers have realised that Type 1 Diabetes could also be consigned to the history books with these advances – they have been devised a way to genetically program the liver to produce the insulin that the body lacks. For people with diabetes, this should mean no more daily injections and finger-prick sugar tests.

CRISPR also means that we we have a serious chance of healing many types of cancer – or at least keeping them at bay better than ever before. A fantastical new cancer treatment, called CAR-T therapy, sees doctors taking a big slug of a person’s blood, extracting a sample of their immune cells, then genetically programming them to attack their cancer. These super-powered infection-fighters are injected back into the blood so that they set about killing the cancer as if it were a virus. A few days ago, research results showed that it worked against lymphoma (a cancer of the blood) and right now it is being piloted in brain tumours and a host of other cancers.

As exciting as they are, none of these advances have the shock and awe of a Harvey Weinstein sex scandal, so don’t sell papers or get the clicks. Neither do they usually arrive in ‘Eureka!’ apple-dropping breakthrough moments, but from the slow drip-drip-drip of steady progress from countless researchers chipping away at the rockface. It’s going to take patience –many years – until the investment pays out. But these good news stories will probably go on to effect all of our lives, and is certainly a far better bet than any bitcoin.

Thanks for reading. Feel free to add your thoughts and share important news stories that you think slipped under the radar in the comments below.

 

Fireworks image credit: chensiyuan via Wikimedia

Mario turns 30! How playing video games can be good for us (sometimes)

Super MarioHappy Birthday Mario! The large-nosed plumber, famous as Nintendo video game character who jumps down pipes and collects mushrooms, has just turned just turned thirty*. And he now the iconic video game star has a real reason to jump for joy. Research is increasingly showing us that video games could be good for us, which means all of us could benefit from a bit of Mario-time every once in a while.

Originally a tiny 130 pixel graphic, the mustachioed 1985 superhero went on to spawn a franchise worth over $10 million and in 1993 inspired the first Hollywood movie to feature a video game. (Called Mario Bros. it stared Bob Hoskins, but was awful.) Today’s photorealistic games are a far cry from these early days and are no longer the preserve of closeted teenage boys. People of all ages play computer games in their front rooms, often together. This hasn’t stopped parents and doctors being concerned, however, and photorealistic action games tend to cause the most controversy. Read more

Beware the health scan scams: don’t be fooled by the long words

The original Magic 8 BallMagic 8 Ball toys are great fun when you’re a kid. The fortune-telling plastic spheres have been entertaining children since the 1950s and are delightfully simple – you ask the black ball a question, give it a shake, and an answer ‘magically’ emerges out of the inky darkness. “Will I be popular at school?” The ball says: “It is decidedly so.” “Should I ask Debbie to out to the disco?“ The ball replies: “Signs point to yes”. “Will I be a millionaire someday”? “Don’t count on it,” replies the ball. All is not lost, however, for those who aspire after the high life: you can keep shaking until you get the answer you want. Read more

‘Google to rank pages by accuracy’ shown to be inaccurate

Google Knowledge Panel in search resultsAs a science writer who writes a lot about health, I spend more time than most scouring the internet for medicine-related information. Unfortunately, the advice that ‘Dr Google’ prescribes is all-too-often a bit dodgy. Search ‘how to treat my headache’, for example, and in alongside the sensible suggestions are some rather more dubious and laughable ‘natural cures’. Search for answers to child health problems and things get far scarier. A 2010 paper showed that only 39% of the top 500 Google results gave correct information about specific child health questions. Search queries related to mumps, measles and rubella and autism yielded the the most misleading information.

It was exciting, therefore, to learn of Google’s new effort to rid the internet of dodgy advice and quackery. Today, all search results are ranked according to popularity (crudely speaking); dodgy science seen as ‘trustworthy’ by appears toward the top of search rankings, regardless of how erroneous it may be. Published research reveals how Google ‘want to’ organise search results according to their accuracy. Read more

Three parent babies: it’s not what you think

feet in bedMost of us came into this world through a moment of passion between our father and mother. Not so for everyone. In the world today there are 200,000 people who were not conceived in the conventional way – but in a Petri dish. For the past 35 years, IVF (In Vitro Fertilisation) and similar ‘test tube baby’ techniques have transformed the lives of millions of couples with fertility problems, offering them the chance to have children when they otherwise couldn’t. Lauded as one of the greatest achievements of modern medicine, it nevertheless remains controversial. For example, the process often results in fertilised eggs being discarded – something many religious organisations object to. A few weeks ago, however, fertility techniques just became a whole lot more contentious when the UK became the first country in the world to allow three-parent babies. By next year there will probably be children born of two mothers and one father. It sounds truly bizarre but it’s not what you think. Read more

Exercise machine calorie counters: they exaggerate the burn

TreadmillJanuary is the month of the jogger. Every evening for the past three weeks, regular-looking folk have been bouncing their bits up and down our streets, running in the pursuit of getting a bit fitter. No doubt prompted by a New Year’s resolution or ill-considered pledge to run this year’s half-marathon, such noble joggers oftentimes prefer an air-conditioned gym. Away from the wind and snow, the treadmills and ‘cardio’ machines offer music, television and – the greatest motivator of all – the digitised calorie counter. Trundling away on a treadmill while watching ‘Cash in the Attic’ is soul-crushingly dull but the knowledge that twenty minutes of puffing will burn off the a chocolate bar’s worth of calories can help keep your legs pounding. It’s such a shame, then, that the treadmill is lying to you. The truth is that if you want to justify a chocolate indulgence then you’ll probably need to sweat for just a bit longer than the computer tells you. Read more

How to heal paralysis: modern day miracles

Darek FidykaWithout doubt, Geoffrey Raisman is in line for a Nobel Prize. The little-known British professor has been the brains behind a breakthrough that ‘cured’ a paraplegic man. Bulgarian Darek Fidyka was left paralysed after a knife attack four years ago; images of him now standing upright shot across the globe a few weeks ago. For the first time in history, surgeons had successfully fixed a severed spinal cord. In a bizarre act of surgical jiggery-pokery, surgeons removed nerve cells from Darek’s nose and then transplanted into his damaged spinal cord. Once there, the nose cells stimulated nerves to grow across the 8 mm gap in the spinal cord. And amazingly, this ultimately gave him feeling and movement back in his legs. Read more

The curious case of the phantom vibrating phone

Smartphone in your pocketI’ve only been back in the UK a matter of hours and it’s already started. After a few days abroad, I am taking a stroll through the beauty of Wiltshire’s county town to remind myself how good it is to be back in good ol’ Blighty. And then suddenly – and without warning – my reverie is broken by a vibrating right thigh. It is the tell-tale buzz of my mobile phone, which has now awoken from its vacation slumber. A text message or twitter update perhaps? Neither, as it happens. For when I have prised my phone out from my (now slightly tighter) jeans pocket, I see that the screen is blank. No message, no twitter update and no new email – nichts, nada… nobody loves me today. And yet the sensation was unmistakably real. But, I am not going mad; for this, dear reader, is another case of the ‘phantom phone vibration’. Read more

Take the smartphone addiction test! Are you hooked to your iPhone?

C3GZ by Symic, on FlickrIt’s dinner time and the log fire is burning. My wife and I sitting in a pub on a rainy day and we are eyeing the menus – the seafood looks nice. Yes, this is the stuff of an English holiday by the sea: sitting on wooden chairs near an open fire with harassed-looking bar staff in one corner and a gambling machine in the other.

A family dressed in matching waterproof coats – clearly also on their holiday – take seats next to us. That’s odd, I think, there’s none of the usual sibling squabbling between the kids. No, this family is calm and contented because two of the school age kids are on their smartphones. And so are both the parents. Meanwhile, the six year old is playing on a Gameboy.
Read more

I can’t tweet without you: How twitter feeds our inner longing for friendship

CreativeTools.se - Twitter bird standing on branch - Close-up by Creative Tools, on FlickrI think I’ve started to feel what it’s like to get old. Strange ‘#’ symbols started to flash up on the TV screen a few months back. Some odd new lottery I wondered? Oblivious to the newest and most important media advancement in the last decade, my friends laughed at my ignorance. Graciously educating me in twitter-speak, they taught me what ‘followers’, @ symbols, retweets and trends were. Since 1988 when an 8-bit Commodore 64 arrived in Christmas gift wrap, I have prided myself in being up to date with tech-culture. It seemed much easier when Mario was a child.

Although I am now twitter fluent, and a regular user, try as I may, I don’t get very excited about it. Like Facebook, it feels a chore – akin to laborious Christmas-card-writing – a necessity to stay digitally ‘connected’. Surely I am in the minority: of twitter’s 140 million (and growing) users, most surely use social media for the joy of it – delighting in sharing life’s experiences day, night and through those crafty under-the-table tweets. Read more